General Structure Information
| PDB ID | 3zwf |
| HGNC Gene Label(s) | ELAC1 |
| Structure Name | crystal structure of human trnase z, short form (elac1). |
| Resolution | 1.7Å |
| Reference | AUTH C.K.ALLERSTON,T.KROJER,G.BERRIDGE,N.BURGESS-BROWN,AUTH 2 A.CHAIKUAD,R.CHALK,J.M.ELKINS,C.GILEADI,S.V.A.LATWIEL,AUTH 3 P.SAVITSKY,M.VOLLMAR,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,AUTH 4 C.BOUNTRA,F.VON DELFT,O.GILEADITITL CRYSTAL STRUCTURE OF HUMAN TRNASE Z, SHORT FORM (ELAC1).REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 259 |
| Number Of SNVs | 67 |
| Number Of Permutations | 6932 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.127 |
| p-value | 0.882 |
COSMIC
| Number Of Residues | 259 |
| Number Of SNVs | 3 |
| Number Of Permutations | 157 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.333 |
| p-value | 0.478 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.503 |
| p-value | 0.201 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
