General Structure Information
| PDB ID | 1p9o |
| HGNC Gene Label(s) | PPCS |
| Structure Name | crystal structure of phosphopantothenoylcysteine synthetase |
| Resolution | 2.3Å |
| Reference | AUTH N.MANOJ,E.STRAUSS,T.P.BEGLEY,S.E.EALICKTITL STRUCTURE OF HUMAN PHOSPHOPANTOTHENOYLCYSTEINETITL 2 SYNTHETASE AT 2.3 A RESOLUTION.REF STRUCTURE V. 11 927 2003REFN ISSN 0969-2126PMID 12906824DOI 10.1016/S0969-2126(03)00146-1 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 269 |
| Number Of SNVs | 61 |
| Number Of Permutations | 36706 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.123 |
| p-value | 0.117 |
COSMIC
| Number Of Residues | 269 |
| Number Of SNVs | 3 |
| Number Of Permutations | 154 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.333 |
| p-value | 0.516 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | -0.56 |
| p-value | 0.17 |