General Structure Information
| PDB ID | 3zdk |
| HGNC Gene Label(s) | DCLRE1B |
| Structure Name | crystal structure of human 5 exonuclease apollo |
| Resolution | 2.16Å |
| Reference | AUTH C.K.ALLERSTON,M.VOLLMAR,T.KROJER,A.C.W.PIKE,E.CARPENTER,AUTH 2 A.QUIGLEY,P.MAHAJAN,F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 A.EDWARDS,O.GILEADITITL CRYSTAL STRUCTURE OF HUMAN 5 EXONUCLEASE APOLLOREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 313 |
| Number Of SNVs | 81 |
| Number Of Permutations | 15599 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.276 |
| p-value | 0.001 |
COSMIC
| Number Of Residues | 313 |
| Number Of SNVs | 4 |
| Number Of Permutations | 116 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.167 |
| p-value | 0.677 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 81 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.28 |
| p-value | 0.517 |