3Q2E.A | BRWD1

General Structure Information

PDB ID 3q2e
HGNC Gene Label(s) BRWD1
Structure Name crystal structure of the second bromodomain of human bromodomain and wd repeat-containing protein 1 isoform a (wdr9)
Resolution 1.74Å
Reference AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013

Variant Set Distributions

ExAC Variants

Number Of Residues 107
Number Of SNVs 19
Number Of Permutations 1482
Optimal Distance Threshold 6.0
K Statistic 0.058
p-value 0.902

Mapped Variants

[+] ExAC Missense Variants