General Structure Information
| PDB ID | 2ht9 |
| HGNC Gene Label(s) | GLRX2 |
| Structure Name | the structure of dimeric human glutaredoxin 2 |
| Resolution | 1.9Å |
| Reference | AUTH C.JOHANSSON,K.L.KAVANAGH,O.GILEADI,U.OPPERMANNTITL REVERSIBLE SEQUESTRATION OF ACTIVE SITE CYSTEINES IN ATITL 2 2FE-2S-BRIDGED DIMER PROVIDES A MECHANISM FOR GLUTAREDOXIN 2TITL 3 REGULATION IN HUMAN MITOCHONDRIAREF J.BIOL.CHEM. V. 282 3077 2007REFN ISSN 0021-9258PMID 17121859DOI 10.1074/JBC.M608179200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 111 |
| Number Of SNVs | 25 |
| Number Of Permutations | 1690 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.083 |
| p-value | 0.803 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.63 |
| p-value | 0.142 |