General Structure Information
| PDB ID | 1sl6 |
| HGNC Gene Label(s) | CLEC4M |
| Structure Name | crystal structure of a fragment of dc-signr (containg the carbohydrate recognition domain and two repeats of the neck) complexed with lewis-x. |
| Resolution | 2.25Å |
| Reference | AUTH Y.GUO,H.FEINBERG,E.CONROY,D.A.MITCHELL,R.ALVAREZ,AUTH 2 O.BLIXT,M.E.TAYLOR,W.I.WEIS,K.DRICKAMERTITL STRUCTURAL BASIS FOR DISTINCT LIGAND-BINDING ANDTITL 2 TARGETING PROPERTIES OF THE RECEPTORS DC-SIGN ANDTITL 3 DC-SIGNRREF NAT.STRUCT.MOL.BIOL. V. 11 591 2004REFN ISSN 1545-9993PMID 15195147DOI 10.1038/NSMB784 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 168 |
| Number Of SNVs | 50 |
| Number Of Permutations | 26784 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.11 |
| p-value | 0.198 |
COSMIC
| Number Of Residues | 168 |
| Number Of SNVs | 6 |
| Number Of Permutations | 789 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.267 |
| p-value | 0.285 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.199 |
| p-value | 0.436 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
