General Structure Information
| PDB ID | 4aiw |
| HGNC Gene Label(s) | GLIPR2 |
| Structure Name | gapr-1 with bound inositol hexakisphosphate |
| Resolution | 1.5Å |
| Reference | AUTH J.VAN GALEN,N.K.OLRICHS,A.SCHOUTEN,R.L.SERRANO,AUTH 2 E.N.M.NOLTE-T HOEN,R.EERLAND,D.KALOYANOVA,P.GROS,J.B.HELMSTITL INTERACTION OF GAPR-1 WITH LIPID BILAYERS IS REGULATED BYTITL 2 ALTERNATIVE HOMODIMERIZATION.REF BIOCHIM.BIOPHYS.ACTA V.1818 2175 2012REFN ISSN 0006-3002PMID 22560898DOI 10.1016/J.BBAMEM.2012.04.016 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 150 |
| Number Of SNVs | 40 |
| Number Of Permutations | 3544 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.059 |
| p-value | 0.399 |
COSMIC
| Number Of Residues | 150 |
| Number Of SNVs | 3 |
| Number Of Permutations | 162 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.886 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 40 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.21 |
| p-value | 0.915 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
