General Structure Information
| PDB ID | 4cem |
| HGNC Gene Label(s) | UPF2 |
| Structure Name | crystal structure of the first mif4g domain of human nonsense mediated decay factor upf2 |
| Resolution | 2.6Å |
| Reference | AUTH M.CLERICI,A.DENIAUD,V.BOEHM,N.H.GEHRING,C.SCHAFFITZEL,AUTH 2 S.CUSACKTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE THREE MIF4GTITL 2 DOMAINS OF NONSENSE-MEDIATED DECAY FACTOR UPF2.REF NUCLEIC ACIDS RES. V. 42 2673 2014REFN ISSN 0305-1048PMID 24271394DOI 10.1093/NAR/GKT1197 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 305 |
| Number Of SNVs | 50 |
| Number Of Permutations | 49808 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.04 |
| p-value | 0.331 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.275 |
| p-value | 0.771 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
