General Structure Information
| PDB ID | 2fv7 |
| HGNC Gene Label(s) | RBKS |
| Structure Name | crystal structure of human ribokinase |
| Resolution | 2.1Å |
| Reference | AUTH W.M.RABEH,W.TEMPEL,L.NEDYALKOVA,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARK,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN RIBOKINASEREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 308 |
| Number Of SNVs | 99 |
| Number Of Permutations | 45961 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.199 |
| p-value | 0.174 |
COSMIC
| Number Of Residues | 308 |
| Number Of SNVs | 5 |
| Number Of Permutations | 585 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.2 |
| p-value | 0.84 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 99 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.229 |
| p-value | 0.644 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
