General Structure Information
| PDB ID | 2iqc |
| HGNC Gene Label(s) | FANCF |
| Structure Name | crystal structure of human fancf protein that functions in the assembly of a dna damage signaling complex |
| Resolution | 2.4Å |
| Reference | AUTH P.KOWAL,A.M.GURTAN,P.STUCKERT,A.D.DANDREA,AUTH 2 T.ELLENBERGERTITL STRUCTURAL DETERMINANTS OF HUMAN FANCF PROTEINTITL 2 THAT FUNCTION IN THE ASSEMBLY OF A DNA DAMAGETITL 3 SIGNALING COMPLEX.REF J.BIOL.CHEM. V. 282 2047 2007REFN ISSN 0021-9258PMID 17082180DOI 10.1074/JBC.M608356200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 173 |
| Number Of SNVs | 48 |
| Number Of Permutations | 7363 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.029 |
| p-value | 0.866 |
COSMIC
| Number Of Residues | 173 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2372 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.4 |
| p-value | 0.62 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.319 |
| p-value | 0.698 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
