General Structure Information
| PDB ID | 2y9t |
| HGNC Gene Label(s) | TP63 |
| Structure Name | structural basis of p63a sam domain mutants involved in aec syndrome |
| Resolution | -1.0Å |
| Reference | AUTH A.SATHYAMURTHY,S.M.V.FREUND,C.M.JOHNSON,M.D.ALLEN,M.BYCROFTTITL STRUCTURAL BASIS OF P63ALPHA SAM DOMAIN MUTANTS INVOLVED INTITL 2 AEC SYNDROME.REF FEBS J. V. 278 2680 2011REFN ISSN 1742-464XPMID 21615690DOI 10.1111/J.1742-4658.2011.08194.X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 80 |
| Number Of SNVs | 16 |
| Number Of Permutations | 1959 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.067 |
| p-value | 0.49 |
ClinVar
| Number Of Residues | 80 |
| Number Of SNVs | 4 |
| Number Of Permutations | 262 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.333 |
| p-value | 0.105 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.3 |
| p-value | 0.074 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
