General Structure Information
| PDB ID | 3tgx |
| HGNC Gene Label(s) | IL21R |
| Structure Name | il-21:il21r complex |
| Resolution | 2.8Å |
| Reference | AUTH O.J.HAMMING,L.KANG,A.SVENSSON,J.L.KARLSEN,H.RAHBEK-NIELSEN,AUTH 2 S.R.PALUDAN,S.A.HJORTH,K.BONDENSGAARD,R.HARTMANNTITL THE CRYSTAL STRUCTURE OF THE INTERLEUKIN 21 RECEPTOR BOUNDTITL 2 TO INTERLEUKIN 21 REVEALS THAT A SUGAR CHAIN INTERACTINGTITL 3 WITH THE WSXWS MOTIF IS AN INTEGRAL PART OF THE INTERLEUKINTITL 4 21 RECEPTOR.REF J.BIOL.CHEM. 2012REFN ESSN 1083-351XPMID 22235133DOI 10.1074/JBC.M111.311084 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 209 |
| Number Of SNVs | 51 |
| Number Of Permutations | 37214 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.024 |
| p-value | 0.996 |
COSMIC
| Number Of Residues | 209 |
| Number Of SNVs | 3 |
| Number Of Permutations | 159 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.667 |
| p-value | 0.65 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 51 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.467 |
| p-value | 0.647 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
