General Structure Information
| PDB ID | 4kt1 |
| HGNC Gene Label(s) | LGR4 |
| Structure Name | complex of r-spondin 1 with lgr4 extracellular domain |
| Resolution | 2.5Å |
| Reference | AUTH D.L.WANG,B.HUANG,S.ZHANG,X.YU,W.WU,X.Q.WANGTITL STRUCTURAL BASIS FOR R-SPONDIN RECOGNITION BY LGR4/5/6TITL 2 RECEPTORSREF GENES DEV. V. 27 1339 2013REFN ISSN 0890-9369PMID 23756652DOI 10.1101/GAD.219360.113 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 459 |
| Number Of SNVs | 84 |
| Number Of Permutations | 54256 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.371 |
| p-value | 0.361 |
COSMIC
| Number Of Residues | 459 |
| Number Of SNVs | 5 |
| Number Of Permutations | 403 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.2 |
| p-value | 0.188 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 42.0 |
| K Statistic | 0.385 |
| p-value | 0.185 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
