General Structure Information
| PDB ID | 3hai |
| HGNC Gene Label(s) | PACSIN1 |
| Structure Name | crystal structure of human pacsin1 f-bar domain (p21 lattice) |
| Resolution | 2.88Å |
| Reference | AUTH Q.WANG,M.V.NAVARRO,G.PENG,E.MOLINELLI,S.LIN GOH,AUTH 2 B.L.JUDSON,K.R.RAJASHANKAR,H.SONDERMANNTITL MOLECULAR MECHANISM OF MEMBRANE CONSTRICTION ANDTITL 2 TUBULATION MEDIATED BY THE F-BAR PROTEINTITL 3 PACSIN/SYNDAPIN.REF PROC.NATL.ACAD.SCI.USA V. 106 12700 2009REFN ISSN 0027-8424PMID 19549836DOI 10.1073/PNAS.0902974106 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 294 |
| Number Of SNVs | 48 |
| Number Of Permutations | 67786 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.12 |
| p-value | 0.303 |
COSMIC
| Number Of Residues | 294 |
| Number Of SNVs | 3 |
| Number Of Permutations | 924 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.878 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.316 |
| p-value | 0.816 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
