General Structure Information
| PDB ID | 4i1o |
| HGNC Gene Label(s) | RAB1B |
| Structure Name | crystal structure of the legionella pneumophila gap domain of lepb in complex with rab1b bound to gdp and bef3 |
| Resolution | 2.7Å |
| Reference | AUTH E.MIHAI GAZDAG,A.STRELLER,I.HANEBURGER,H.HILBI,I.R.VETTER,AUTH 2 R.S.GOODY,A.ITZENTITL MECHANISM OF RAB1B DEACTIVATION BY THE LEGIONELLATITL 2 PNEUMOPHILA GAP LEPB.REF EMBO REP. V. 14 199 2013REFN ISSN 1469-221XPMID 23288104DOI 10.1038/EMBOR.2012.211 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 171 |
| Number Of SNVs | 23 |
| Number Of Permutations | 7100 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.071 |
| p-value | 0.747 |
COSMIC
| Number Of Residues | 171 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
