2HEH.A | KIF2C

General Structure Information

PDB ID 2heh
HGNC Gene Label(s) KIF2C
Structure Name crystal structure of the kif2c motor domain (casp target)
Resolution 2.15Å
Reference AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE KIF2C MOTOR DOMAINREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 324
Number Of SNVs 71
Number Of Permutations 47447
Optimal Distance Threshold 6.0
K Statistic 0.019
p-value 0.224
COSMIC

Number Of Residues 324
Number Of SNVs 3
Number Of Permutations 243
Optimal Distance Threshold 29.0
K Statistic 0.333
p-value 0.779

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants