General Structure Information
| PDB ID | 3qrf |
| HGNC Gene Label(s) | FOXP3 |
| Structure Name | structure of a domain-swapped foxp3 dimer |
| Resolution | 2.8Å |
| Reference | AUTH H.S.BANDUKWALA,Y.WU,M.FEUERER,Y.CHEN,B.BARBOZA,S.GHOSH,AUTH 2 J.C.STROUD,C.BENOIST,D.MATHIS,A.RAO,L.CHENTITL STRUCTURE OF A DOMAIN-SWAPPED FOXP3 DIMER ON DNA AND ITSTITL 2 FUNCTION IN REGULATORY T CELLS.REF IMMUNITY V. 34 479 2011REFN ISSN 1074-7613PMID 21458306DOI 10.1016/J.IMMUNI.2011.02.017 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 82 |
| Number Of SNVs | 4 |
| Number Of Permutations | 243 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.892 |
ClinVar
| Number Of Residues | 82 |
| Number Of SNVs | 5 |
| Number Of Permutations | 356 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.4 |
| p-value | 0.27 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 4 |
| Number Of ClinVar SNVs | 5 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.678 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
