General Structure Information
| PDB ID | 4frw |
| HGNC Gene Label(s) | PVRL4 |
| Structure Name | crystal structure of human nectin-4 extracellular fragment d1-d2 |
| Resolution | 3.5Å |
| Reference | AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 212 |
| Number Of SNVs | 53 |
| Number Of Permutations | 14240 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.554 |
| p-value | 0.195 |
COSMIC
| Number Of Residues | 212 |
| Number Of SNVs | 5 |
| Number Of Permutations | 26 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.1 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.392 |
| p-value | 0.564 |