General Structure Information
| PDB ID | 2ag5 |
| HGNC Gene Label(s) | BDH2 |
| Structure Name | crystal structure of human dhrs6 |
| Resolution | 1.84Å |
| Reference | AUTH K.GUO,P.LUKACIK,E.PAPAGRIGORIOU,M.MEIER,W.H.LEE,J.ADAMSKI,AUTH 2 U.OPPERMANNTITL CHARACTERIZATION OF HUMAN DHRS6, AN ORPHAN SHORT CHAINTITL 2 DEHYDROGENASE/REDUCTASE ENZYME: A NOVEL, CYTOSOLIC TYPE 2TITL 3 R-BETA-HYDROXYBUTYRATE DEHYDROGENASEREF J.BIOL.CHEM. V. 281 10291 2006REFN ISSN 0021-9258PMID 16380372DOI 10.1074/JBC.M511346200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 245 |
| Number Of SNVs | 58 |
| Number Of Permutations | 23714 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.034 |
| p-value | 0.246 |
COSMIC
| Number Of Residues | 245 |
| Number Of SNVs | 6 |
| Number Of Permutations | 971 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.133 |
| p-value | 0.397 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 58 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.094 |
| p-value | 0.663 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
