General Structure Information
| PDB ID | 3o4r |
| HGNC Gene Label(s) | DHRS4 |
| Structure Name | crystal structure of human dehydrogenase/reductase (sdr family) member 4 (dhrs4) |
| Resolution | 1.7Å |
| Reference | AUTH E.UGOCHUKWU,C.BHATIA,T.KROJER,M.VOLLMAR,W.W.YUE,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,F.VON DELFT,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN DEHYDROGENASE/REDUCTASE (SDRTITL 2 FAMILY) MEMBER 4 (DHRS4)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 252 |
| Number Of SNVs | 51 |
| Number Of Permutations | 21245 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.331 |
| p-value | 0.112 |
COSMIC
| Number Of Residues | 252 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1065 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.167 |
| p-value | 0.966 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 51 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.105 |
| p-value | 0.842 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
