General Structure Information
| PDB ID | 3op5 |
| HGNC Gene Label(s) | VRK1 |
| Structure Name | human vaccinia-related kinase 1 |
| Resolution | 2.4Å |
| Reference | AUTH C.K.ALLERSTON,S.UTTARKAR,P.SAVITSKY,J.M.ELKINS,AUTH 2 P.FILIPPAKOPOULOS,T.KROJER,P.RELLOS,O.FEDOROV,J.ESWARAN,AUTH 3 B.BRENNER,T.KEATES,S.DAS,O.KING,R.CHALK,G.BERRIDGE,AUTH 4 F.VON DELFT,O.GILEADI,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 5 C.BOUNTRA,S.KNAPPTITL HUMAN VACCINIA-RELATED KINASE 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 308 |
| Number Of SNVs | 64 |
| Number Of Permutations | 11322 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.019 |
| p-value | 0.592 |
ClinVar
| Number Of Residues | 308 |
| Number Of SNVs | 3 |
| Number Of Permutations | 173 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.0 |
| p-value | 0.639 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 64 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.294 |
| p-value | 0.536 |