General Structure Information
| PDB ID | 2l9r |
| HGNC Gene Label(s) | NKX3-1 |
| Structure Name | solution nmr structure of homeobox domain of homeobox protein nkx-3.1 from homo sapiens, northeast structural genomics consortium target hr6470a |
| Resolution | -1.0Å |
| Reference | AUTH G.LIU,R.XIAO,H.-W.LEE,K.HAMILTON,C.CICCOSANTI,H.B.WANG,AUTH 2 T.B.ACTON,J.K.EVERETT,Y.J.HUANG,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF HOMEOBOX DOMAIN OF HOMEOBOXTITL 2 PROTEIN NKX-3.1 FROM HOMO SAPIENS, NORTHEAST STRUCTURALTITL 3 GENOMICS CONSORTIUM TARGET HR6470AREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 58 |
| Number Of SNVs | 12 |
| Number Of Permutations | 2715 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.197 |
| p-value | 0.431 |
COSMIC
| Number Of Residues | 58 |
| Number Of SNVs | 4 |
| Number Of Permutations | 168 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 0.265 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 12 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.212 |
| p-value | 0.418 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
