General Structure Information
| PDB ID | 2d9q |
| HGNC Gene Label(s) | CSF3R |
| Structure Name | crystal structure of the human gcsf-receptor signaling complex |
| Resolution | 2.8Å |
| Reference | AUTH T.TAMADA,E.HONJO,Y.MAEDA,T.OKAMOTO,M.ISHIBASHI,M.TOKUNAGA,AUTH 2 R.KUROKITITL HOMODIMERIC CROSS-OVER STRUCTURE OF THE HUMAN GRANULOCYTETITL 2 COLONY-STIMULATING FACTOR (GCSF) RECEPTOR SIGNALING COMPLEXREF PROC.NATL.ACAD.SCI.USA V. 103 3135 2006REFN ISSN 0027-8424PMID 16492764DOI 10.1073/PNAS.0511264103 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 299 |
| Number Of SNVs | 74 |
| Number Of Permutations | 61732 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.333 |
| p-value | 0.026 |
COSMIC
| Number Of Residues | 299 |
| Number Of SNVs | 4 |
| Number Of Permutations | 826 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.167 |
| p-value | 0.801 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 74 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | -0.31 |
| p-value | 0.411 |