General Structure Information
| PDB ID | 2rlo |
| HGNC Gene Label(s) | AGAP2 |
| Structure Name | split ph domain of pi3-kinase enhancer |
| Resolution | -1.0Å |
| Reference | AUTH J.YAN,W.WEN,L.N.CHAN,M.ZHANGTITL SPLIT PLECKSTRIN HOMOLOGY DOMAIN-MEDIATEDTITL 2 CYTOPLASMIC-NUCLEAR LOCALIZATION OF PI3-KINASETITL 3 ENHANCER GTPASEREF J.MOL.BIOL. V. 378 425 2008REFN ISSN 0022-2836PMID 18371979DOI 10.1016/J.JMB.2008.02.052 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 128 |
| Number Of SNVs | 9 |
| Number Of Permutations | 1193 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.0 |
| p-value | 0.484 |
COSMIC
| Number Of Residues | 128 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.902 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 9 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.194 |
| p-value | 0.74 |