General Structure Information
| PDB ID | 2pqf |
| HGNC Gene Label(s) | PARP12 |
| Structure Name | human poly(adp-ribose) polymerase 12, catalytic fragment in complex with an inhibitor 3-aminobenzoic acid |
| Resolution | 2.2Å |
| Reference | AUTH T.KARLBERG,M.KLEPSCH,A.G.THORSELL,C.D.ANDERSSON,A.LINUSSON,AUTH 2 H.SCHULERTITL STRUCTURAL BASIS FOR LACK OF ADP-RIBOSYLTRANSFERASE ACTIVITYTITL 2 IN POLY(ADP-RIBOSE) POLYMERASE-13/ZINC FINGER ANTIVIRALTITL 3 PROTEIN.REF J.BIOL.CHEM. V. 290 7336 2015REFN ISSN 0021-9258PMID 25635049DOI 10.1074/JBC.M114.630160 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 179 |
| Number Of SNVs | 47 |
| Number Of Permutations | 21642 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.043 |
| p-value | 0.556 |
COSMIC
| Number Of Residues | 179 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.371 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
