General Structure Information
| PDB ID | 1y97 |
| HGNC Gene Label(s) | TREX2 |
| Structure Name | the human trex2 3 exonuclease structure suggests a mechanism for efficient non-processive dna catalysis |
| Resolution | 2.5Å |
| Reference | AUTH F.W.PERRINO,S.HARVEY,S.MCMILLIN,T.HOLLISTITL THE HUMAN TREX2 3 -> 5-EXONUCLEASE STRUCTURETITL 2 SUGGESTS A MECHANISM FOR EFFICIENT NONPROCESSIVETITL 3 DNA CATALYSIS.REF J.BIOL.CHEM. V. 280 15212 2005REFN ISSN 0021-9258PMID 15661738DOI 10.1074/JBC.M500108200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 209 |
| Number Of SNVs | 50 |
| Number Of Permutations | 5192 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.062 |
| p-value | 0.015 |
COSMIC
| Number Of Residues | 209 |
| Number Of SNVs | 3 |
| Number Of Permutations | 184 |
| Optimal Distance Threshold | 38.0 |
| K Statistic | 0.667 |
| p-value | 0.349 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
