General Structure Information
| PDB ID | 2cn1 |
| HGNC Gene Label(s) | NT5C3A |
| Structure Name | crystal structure of human cytosolic 5-nucleotidase iii ( nt5c3)(casp target) |
| Resolution | 2.67Å |
| Reference | AUTH K.WALLDEN,P.STENMARK,T.NYMAN,S.FLODIN,S.GRASLUND,P.LOPPNAU,AUTH 2 V.BIANCHI,P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5-NUCLEOTIDASE II:TITL 2 INSIGHTS INTO ALLOSTERIC REGULATION AND SUBSTRATETITL 3 RECOGNITION.REF J.BIOL.CHEM. V. 282 17828 2007REFN ISSN 0021-9258PMID 17405878DOI 10.1074/JBC.M700917200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 273 |
| Number Of SNVs | 67 |
| Number Of Permutations | 8786 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.153 |
| p-value | 0.147 |
ClinVar
| Number Of Residues | 273 |
| Number Of SNVs | 3 |
| Number Of Permutations | 157 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.81 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.445 |
| p-value | 0.739 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
