General Structure Information
| PDB ID | 2rep |
| HGNC Gene Label(s) | KIFC1 |
| Structure Name | crystal structure of the motor domain of human kinesin family member c1 |
| Resolution | 2.6Å |
| Reference | AUTH H.ZHU,W.TEMPEL,H.HE,Y.SHEN,J.WANG,G.BROTHERS,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESINTITL 2 FAMILY MEMBER C1.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 289 |
| Number Of SNVs | 68 |
| Number Of Permutations | 34933 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.253 |
| p-value | 0.05 |
COSMIC
| Number Of Residues | 289 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.316 |
| p-value | 0.901 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
