General Structure Information
| PDB ID | 2km6 |
| HGNC Gene Label(s) | NLRP7 |
| Structure Name | nmr structure of the nlrp7 pyrin domain |
| Resolution | -1.0Å |
| Reference | AUTH A.S.PINHEIRO,M.PROELL,C.EIBL,R.PAGE,R.SCHWARZENBACHER,W.PETITITL THREE-DIMENSIONAL STRUCTURE OF THE NLRP7 PYRIN DOMAIN:TITL 2 INSIGHT INTO PYRIN-PYRIN-MEDIATED EFFECTOR DOMAIN SIGNALINGTITL 3 IN INNATE IMMUNITY.REF J.BIOL.CHEM. V. 285 27402 2010REFN ISSN 0021-9258PMID 20547486DOI 10.1074/JBC.M110.113191 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 96 |
| Number Of SNVs | 19 |
| Number Of Permutations | 3427 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.111 |
| p-value | 0.949 |
COSMIC
| Number Of Residues | 96 |
| Number Of SNVs | 5 |
| Number Of Permutations | 262 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.1 |
| p-value | 0.759 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 19 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.181 |
| p-value | 0.424 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
