2BK8.A | TTN – ASTRID

2BK8.A | TTN

PDB ID	2bk8
HGNC Gene Label(s)	TTN
Structure Name	m1 domain from titin
Resolution	1.69Å
Reference	AUTH S.MUELLER,I.KURSULA,M.WILMANNSTITL STRUCTURE OF M1 DOMAIN FROM TITINREF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:179398929		V>A	A:3	(23.82, -2.51, 19.68)
2:179398918	rs528796532	I>L	A:7	(25.71, -7.37, 30.74)
2:179398914	rs397517786	M>T	A:8	(28.61, -10.95, 32.29)
2:179398915	rs371226574	M>L	A:8	(28.61, -10.95, 32.29)
2:179398912	rs560027565	H>Y	A:9	(25.24, -13.07, 35.01)
2:179398909	rs542891030	A>T	A:10	(27.15, -11.37, 39.60)
2:179398897		E>K	A:14	(26.02, -9.83, 52.97)
2:179398893		G>E	A:15	(29.09, -5.50, 52.00)
2:179398891	rs191522469	G>R	A:16	(29.88, -5.35, 49.13)
2:179398855		D>N	A:28	(25.33, 9.44, 19.01)
2:179398834		W>R	A:35	(22.26, 0.75, 34.27)
2:179398824		G>D	A:38	(13.73, -3.97, 38.12)
2:179398822	rs200430493	V>I	A:39	(10.44, -1.91, 38.81)
2:179398818	rs201954720	R>Q	A:40	(13.06, -0.28, 42.48)
2:179398813		L>M	A:42	(18.88, 3.18, 39.14)
2:179398810		E>Q	A:43	(19.54, 8.25, 41.14)
2:179398792	COSM208410 COSM208411 COSM3570501 COSM208409 COSM3570502	E>K	A:49	(29.74, 4.52, 41.03)
2:179398785		T>I	A:51	(29.51, 6.04, 34.64)
2:179398780	rs577667352 COSM3570500 COSM3570499 COSM3570496 COSM3570498 COSM3570497	E>K	A:53	(32.44, 8.31, 29.62)
2:179398762		L>I	A:59	(26.17, -0.21, 37.69)
2:179398748		D>E	A:63	(26.75, -1.24, 50.88)
2:179398745		I>M	A:64	(25.50, -5.93, 48.73)
2:179398747	rs56347248	I>V	A:64	(25.50, -5.93, 48.73)
2:179398732		D>N	A:69	(18.91, -11.13, 44.34)
2:179398728	rs367926247	G>D	A:70	(18.37, -9.81, 40.51)
2:179398704	rs375332499	N>S	A:78	(19.27, 7.29, 19.99)
2:179398685	rs370077023	S>R	A:84	(18.11, -3.26, 26.29)
2:179398684		S>A	A:85	(21.03, -5.22, 28.10)
2:179398660	rs555664963	G>R	A:93	(19.97, -17.00, 50.67)