General Structure Information
| PDB ID | 2qfz |
| HGNC Gene Label(s) | TBC1D22A |
| Structure Name | crystal structure of human tbc1 domain family member 22a |
| Resolution | 2.1Å |
| Reference | AUTH Y.TONG,W.TEMPEL,S.DIMOV,A.DONG,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN TBC1 DOMAIN FAMILYTITL 2 MEMBER 22A.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 299 |
| Number Of SNVs | 70 |
| Number Of Permutations | 12181 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.13 |
| p-value | 0.795 |
COSMIC
| Number Of Residues | 299 |
| Number Of SNVs | 6 |
| Number Of Permutations | 562 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.067 |
| p-value | 0.289 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 70 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.046 |
| p-value | 0.416 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
