General Structure Information
| PDB ID | 2peh |
| HGNC Gene Label(s) | RBM17 |
| Structure Name | crystal structure of the uhm domain of human spf45 in complex with sf3b155-ulm5 |
| Resolution | 2.11Å |
| Reference | AUTH L.CORSINI,S.BONNA,J.BASQUIN,M.HOTHORN,K.SCHEFFZEK,AUTH 2 J.VALCARCEL,M.SATTLERTITL U2AF-HOMOLOGY MOTIF INTERACTIONS ARE REQUIRED FORTITL 2 ALTERNATIVE SPLICING REGULATION BY SPF45.REF NAT.STRUCT.MOL.BIOL. V. 14 620 2007REFN ISSN 1545-9993PMID 17589525DOI 10.1038/NSMB1260 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 101 |
| Number Of SNVs | 4 |
| Number Of Permutations | 298 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.0 |
| p-value | 0.47 |
COSMIC
| Number Of Residues | 101 |
| Number Of SNVs | 5 |
| Number Of Permutations | 291 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.1 |
| p-value | 0.927 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 4 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.167 |
| p-value | 0.803 |