General Structure Information
| PDB ID | 3bl7 |
| HGNC Gene Label(s) | DCPS |
| Structure Name | synthetic gene encoded dcps bound to inhibitor dg156844 |
| Resolution | 2.31Å |
| Reference | AUTH J.SINGH,M.SALCIUS,S.W.LIU,B.L.STAKER,R.MISHRA,AUTH 2 J.THURMOND,G.MICHAUD,D.R.MATTOON,J.PRINTEN,AUTH 3 J.CHRISTENSEN,J.M.BJORNSSON,B.A.POLLOK,M.KILEDJIAN,AUTH 4 L.STEWART,J.JARECKI,M.E.GURNEYTITL DCPS AS A THERAPEUTIC TARGET FOR SPINAL MUSCULARTITL 2 ATROPHY.REF ACS CHEM.BIOL. V. 3 711 2008REFN ISSN 1554-8929PMID 18839960DOI 10.1021/CB800120T |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 289 |
| Number Of SNVs | 87 |
| Number Of Permutations | 16188 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.343 |
| p-value | 0.099 |
COSMIC
| Number Of Residues | 289 |
| Number Of SNVs | 4 |
| Number Of Permutations | 279 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 0.577 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.129 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
