General Structure Information
| PDB ID | 2gw6 |
| HGNC Gene Label(s) | TSEN15 |
| Structure Name | nmr structure of the human trna endonuclease sen15 subunit |
| Resolution | -1.0Å |
| Reference | AUTH J.SONG,J.L.MARKLEYTITL THREE-DIMENSIONAL STRUCTURE DETERMINED FOR ATITL 2 SUBUNIT OF HUMAN TRNA SPLICING ENDONUCLEASETITL 3 (SEN15) REVEALS A NOVEL DIMERIC FOLD.REF J.MOL.BIOL. V. 366 155 2007REFN ISSN 0022-2836PMID 17166513DOI 10.1016/J.JMB.2006.11.024 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 122 |
| Number Of SNVs | 22 |
| Number Of Permutations | 2184 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.1 |
| p-value | 0.421 |
COSMIC
| Number Of Residues | 122 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.837 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.359 |
| p-value | 0.48 |