General Structure Information
| PDB ID | 2jk9 |
| HGNC Gene Label(s) | SPSB1 |
| Structure Name | the structure of spla-ryanodine receptor domain and socs box containing 1 in complex with a par-4 peptide |
| Resolution | 1.79Å |
| Reference | AUTH P.FILIPPAKOPOULOS,A.LOW,T.D.SHARPE,J.UPPENBERG,S.YAO,AUTH 2 Z.KUANG,P.SAVITSKY,R.S.LEWIS,S.E.NICHOLSON,R.S.NORTON,AUTH 3 A.BULLOCKTITL STRUCTURAL BASIS FOR PAR-4 RECOGNITION BY THE SPRY DOMAIN-TITL 2 AND SOCS BOX-CONTAINING PROTEINS SPSB1, SPSB2, AND SPSB4.REF J.MOL.BIOL. V. 401 389 2010REFN ISSN 0022-2836PMID 20561531DOI 10.1016/J.JMB.2010.06.017 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 202 |
| Number Of SNVs | 33 |
| Number Of Permutations | 19453 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.28 |
| p-value | 0.377 |
COSMIC
| Number Of Residues | 202 |
| Number Of SNVs | 4 |
| Number Of Permutations | 81 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.167 |
| p-value | 0.57 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.288 |
| p-value | 0.339 |