General Structure Information
| PDB ID | 2qep |
| HGNC Gene Label(s) | PTPRN2 |
| Structure Name | crystal structure of the d1 domain of ptprn2 (ia2beta) |
| Resolution | 2.5Å |
| Reference | AUTH A.J.BARR,E.UGOCHUKWU,W.H.LEE,O.N.KING,P.FILIPPAKOPOULOS,AUTH 2 I.ALFANO,P.SAVITSKY,N.A.BURGESS-BROWN,S.MULLER,S.KNAPPTITL LARGE-SCALE STRUCTURAL ANALYSIS OF THE CLASSICAL HUMANTITL 2 PROTEIN TYROSINE PHOSPHATOME.REF CELL(CAMBRIDGE,MASS.) V. 136 352 2009REFN ISSN 0092-8674PMID 19167335DOI 10.1016/J.CELL.2008.11.038 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 286 |
| Number Of SNVs | 73 |
| Number Of Permutations | 36147 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.019 |
| p-value | 0.723 |
COSMIC
| Number Of Residues | 286 |
| Number Of SNVs | 8 |
| Number Of Permutations | 4625 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.321 |
| p-value | 0.48 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 73 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.089 |
| p-value | 0.639 |