General Structure Information
| PDB ID | 2yt4 |
| HGNC Gene Label(s) | DGCR8 |
| Structure Name | crystal structure of human dgcr8 core |
| Resolution | 2.6Å |
| Reference | AUTH S.Y.SOHN,W.J.BAE,J.J.KIM,K.H.YEOM,V.N.KIM,Y.CHOTITL CRYSTAL STRUCTURE OF HUMAN DGCR8 COREREF NAT.STRUCT.MOL.BIOL. V. 14 847 2007REFN ISSN 1545-9993PMID 17704815DOI 10.1038/NSMB1294 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 192 |
| Number Of SNVs | 21 |
| Number Of Permutations | 3949 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.129 |
| p-value | 0.077 |
COSMIC
| Number Of Residues | 192 |
| Number Of SNVs | 5 |
| Number Of Permutations | 436 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.983 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 21 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.076 |
| p-value | 0.622 |