General Structure Information
| PDB ID | 2vn8 |
| HGNC Gene Label(s) | RTN4IP1 |
| Structure Name | crystal structure of human reticulon 4 interacting protein 1 in complex with nadph |
| Resolution | 2.1Å |
| Reference | AUTH A.C.W.PIKE,K.GUO,J.ELKINS,E.UGOCHUKWU,A.K.ROOS,AUTH 2 P.FILIPPAKOPOULOS,F.VON DELFT,A.EDWARDS,C.H.ARROWSMITH,AUTH 3 J.WEIGELT,C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN RETICULON 4 INTERACTING PROTEINTITL 2 1 IN COMPLEX WITH NADPHREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 352 |
| Number Of SNVs | 92 |
| Number Of Permutations | 38238 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.012 |
| p-value | 0.809 |
COSMIC
| Number Of Residues | 352 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 92 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.39 |
| p-value | 0.587 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
