General Structure Information
| PDB ID | 2rkb |
| HGNC Gene Label(s) | SDSL |
| Structure Name | serine dehydratase like-1 from human cancer cells |
| Resolution | 2.8Å |
| Reference | AUTH T.YAMADA,J.KOMOTO,T.KASUYA,Y.TAKATA,H.OGAWA,H.MORI,AUTH 2 F.TAKUSAGAWATITL A CATALYTIC MECHANISM THAT EXPLAINS A LOW CATALYTIC ACTIVITYTITL 2 OF SERINE DEHYDRATASE LIKE-1 FROM HUMAN CANCER CELLS:TITL 3 CRYSTAL STRUCTURE AND SITE-DIRECTED MUTAGENESIS STUDIES.REF BIOCHIM.BIOPHYS.ACTA V.1780 809 2008REFN ISSN 0006-3002PMID 18342636DOI 10.1016/J.BBAGEN.2008.01.020 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 318 |
| Number Of SNVs | 87 |
| Number Of Permutations | 11797 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.129 |
| p-value | 0.039 |
COSMIC
| Number Of Residues | 318 |
| Number Of SNVs | 4 |
| Number Of Permutations | 276 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.5 |
| p-value | 0.226 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.345 |
| p-value | 0.468 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
