General Structure Information
| PDB ID | 1z4r |
| HGNC Gene Label(s) | KAT2A |
| Structure Name | human gcn5 acetyltransferase |
| Resolution | 1.74Å |
| Reference | AUTH A.SCHUETZ,G.BERNSTEIN,A.DONG,T.ANTOSHENKO,H.WU,AUTH 2 P.LOPPNAU,A.BOCHKAREV,A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF A BINARY COMPLEX BETWEENTITL 2 HUMAN GCN5 HISTONE ACETYLTRANSFERASE DOMAIN ANDTITL 3 ACETYL COENZYME AREF PROTEINS V. 68 403 2007REFN ISSN 0887-3585PMID 17410582DOI 10.1002/PROT.21407 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 162 |
| Number Of SNVs | 32 |
| Number Of Permutations | 2832 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.032 |
| p-value | 0.73 |
COSMIC
| Number Of Residues | 162 |
| Number Of SNVs | 4 |
| Number Of Permutations | 145 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 0.197 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.62 |
| p-value | 0.051 |