General Structure Information
| PDB ID | 1ya0 |
| HGNC Gene Label(s) | SMG7 |
| Structure Name | crystal structure of the n-terminal domain of human smg7 |
| Resolution | 2.55Å |
| Reference | AUTH N.FUKUHARA,J.EBERT,L.UNTERHOLZNER,D.LINDNER,AUTH 2 E.IZAURRALDE,E.CONTITITL SMG7 IS A 14-3-3-LIKE ADAPTOR IN THETITL 2 NONSENSE-MEDIATED MRNA DECAY PATHWAY.REF MOL.CELL V. 17 537 2005REFN ISSN 1097-2765PMID 15721257DOI 10.1016/J.MOLCEL.2005.01.010 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 458 |
| Number Of SNVs | 61 |
| Number Of Permutations | 19994 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.012 |
| p-value | 0.383 |
COSMIC
| Number Of Residues | 458 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1512 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.167 |
| p-value | 0.882 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 41.0 |
| K Statistic | -0.363 |
| p-value | 0.569 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
