General Structure Information
| PDB ID | 3whd |
| HGNC Gene Label(s) | CLEC4D |
| Structure Name | c-type lectin, human mcl |
| Resolution | 2.29Å |
| Reference | AUTH A.FURUKAWA,J.KAMISHIKIRYO,D.MORI,K.TOYONAGA,Y.OKABE,A.TOJI,AUTH 2 R.KANDA,Y.MIYAKE,T.OSE,S.YAMASAKI,K.MAENAKATITL STRUCTURAL ANALYSIS FOR GLYCOLIPID RECOGNITION BY THE C-TYPETITL 2 LECTINS MINCLE AND MCLREF PROC.NATL.ACAD.SCI.USA V. 110 17438 2013REFN ISSN 0027-8424PMID 24101491DOI 10.1073/PNAS.1312649110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 145 |
| Number Of SNVs | 51 |
| Number Of Permutations | 7243 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.118 |
| p-value | 1.0 |
COSMIC
| Number Of Residues | 145 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.667 |
| p-value | 0.758 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 51 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.486 |
| p-value | 0.73 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
