General Structure Information
| PDB ID | 4akv |
| HGNC Gene Label(s) | SNX33 |
| Structure Name | crystal structure of human sorting nexin 33 (snx33) |
| Resolution | 2.65Å |
| Reference | AUTH A.OBERHOLZER,D.S.FROESE,T.KROJER,L.SHRESTHA,AUTH 2 P.FILIPPAKOPOULOS,J.R.C.MUNIZ,F.VON DELFT,C.ARROWSMITH,AUTH 3 J.WEIGELT,A.EDWARDS,C.BOUNTRA,W.W.YUETITL STRUCTURE OF HUMAN SORTING NEXIN 33REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 344 |
| Number Of SNVs | 72 |
| Number Of Permutations | 36336 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.292 |
| p-value | 0.33 |
COSMIC
| Number Of Residues | 344 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1657 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.067 |
| p-value | 0.683 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 72 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 33.0 |
| K Statistic | 0.241 |
| p-value | 0.481 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
