General Structure Information
| PDB ID | 2p82 |
| HGNC Gene Label(s) | ATG4A |
| Structure Name | cysteine protease atg4a |
| Resolution | 2.1Å |
| Reference | AUTH J.R.WALKER,T.DAVIS,S.MUJIB,C.BUTLER-COLE,P.J.FINERTY JR.,AUTH 2 J.WEIGELT,M.SUNDSTROM,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 A.BOCHKAREV,S.DHE-PAGANONTITL HUMAN CYSTEINE PROTEASE ATG4AREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 312 |
| Number Of SNVs | 44 |
| Number Of Permutations | 22791 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.068 |
| p-value | 0.36 |
COSMIC
| Number Of Residues | 312 |
| Number Of SNVs | 10 |
| Number Of Permutations | 6970 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.044 |
| p-value | 0.809 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 44 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.209 |
| p-value | 0.37 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
