2LXS.A | CREBBP

General Structure Information

PDB ID 2lxs
HGNC Gene Label(s) CREBBP
Structure Name allosteric communication in the kix domain proceeds through dynamic re-packing of the hydrophobic core
Resolution -1.0Å
Reference AUTH S.BRUSCHWEILER,R.KONRAT,M.TOLLINGERTITL ALLOSTERIC COMMUNICATION IN THE KIX DOMAIN PROCEEDS THROUGHTITL 2 DYNAMIC REPACKING OF THE HYDROPHOBIC CORE.REF ACS CHEM.BIOL. 2013REFN ESSN 1554-8937PMID 23651431DOI 10.1021/CB4002188

Variant Set Distributions

ExAC Variants

Number Of Residues 87
Number Of SNVs 6
Number Of Permutations 1190
Optimal Distance Threshold 7.0
K Statistic 0.0
p-value 0.875

Mapped Variants

[+] ExAC Missense Variants