3F7G.B | BIRC7

General Structure Information

PDB ID 3f7g
HGNC Gene Label(s) BIRC7
Structure Name structure of the bir domain from ml-iap bound to a peptidomimetic
Resolution 2.3Å
Reference AUTH F.COHEN,B.ALICKE,L.O.ELLIOTT,J.A.FLYGARE,T.GONCHAROV,AUTH 2 S.F.KETELTAS,M.C.FRANKLIN,S.FRANKOVITZ,J.P.STEPHAN,V.TSUI,AUTH 3 D.VUCIC,H.WONG,W.J.FAIRBROTHERTITL ORALLY BIOAVAILABLE ANTAGONISTS OF INHIBITOR OF APOPTOSISTITL 2 PROTEINS BASED ON AN AZABICYCLOOCTANE SCAFFOLDREF J.MED.CHEM. V. 52 1723 2009REFN ISSN 0022-2623PMID 19228017DOI 10.1021/JM801450C

Variant Set Distributions

ExAC Variants

Number Of Residues 101
Number Of SNVs 36
Number Of Permutations 14562
Optimal Distance Threshold 14.0
K Statistic 0.275
p-value 0.205

Mapped Variants

[+] ExAC Missense Variants