General Structure Information
| PDB ID | 3ei4 |
| HGNC Gene Label(s) | DDB2 |
| Structure Name | structure of the hsddb1-hsddb2 complex |
| Resolution | 3.3Å |
| Reference | AUTH A.SCRIMA,R.KONICKOVA,B.K.CZYZEWSKI,Y.KAWASAKI,P.D.JEFFREY,AUTH 2 R.GROISMAN,Y.NAKATANI,S.IWAI,N.P.PAVLETICH,N.H.THOMATITL STRUCTURAL BASIS OF UV DNA-DAMAGE RECOGNITION BY THETITL 2 DDB1-DDB2 COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 135 1213 2008REFN ISSN 0092-8674PMID 19109893DOI 10.1016/J.CELL.2008.10.045 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 368 |
| Number Of SNVs | 84 |
| Number Of Permutations | 41751 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.131 |
| p-value | 0.157 |
ClinVar
| Number Of Residues | 368 |
| Number Of SNVs | 3 |
| Number Of Permutations | 236 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 0.723 |
COSMIC
| Number Of Residues | 368 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 0.996 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.221 |
| p-value | 0.616 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.34 |
| p-value | 0.59 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
