General Structure Information
| PDB ID | 3siu |
| HGNC Gene Label(s) | PRPF31 |
| Structure Name | structure of a hprp31-15.5k-u4atac 5 stem loop complex, monomeric form |
| Resolution | 2.63Å |
| Reference | AUTH S.LIU,H.GHALEI,R.LUHRMANN,M.C.WAHLTITL STRUCTURAL BASIS FOR THE DUAL U4 AND U4ATAC SNRNA-BINDINGTITL 2 SPECIFICITY OF SPLICEOSOMAL PROTEIN HPRP31.REF RNA V. 17 1655 2011REFN ISSN 1355-8382PMID 21784869DOI 10.1261/RNA.2690611 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 235 |
| Number Of SNVs | 43 |
| Number Of Permutations | 24071 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.35 |
| p-value | 0.109 |
ClinVar
| Number Of Residues | 235 |
| Number Of SNVs | 3 |
| Number Of Permutations | 238 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.0 |
| p-value | 0.468 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 43 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.369 |
| p-value | 0.36 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
