2EDI.A | UBE2F

PDB ID	2edi
HGNC Gene Label(s)	UBE2F
Structure Name	solution structure of the uq_con domain from human nedd8- conjugating enzyme nce2
Resolution	-1.0Å
Reference	AUTH H.ENDO,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UQ_CON DOMAIN FROM HUMANTITL 2 NEDD8-CONJUGATING ENZYME NCE2REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:238881829		T>I	A:9	(-9.71, -17.26, 12.11)
2:238881832		R>Q	A:10	(-7.53, -20.12, 5.77)
2:238881850		D>A	A:16	(0.26, -13.35, 0.33)
2:238896610		A>T	A:24	(5.98, -5.68, -7.23)
2:238896623		A>V	A:28	(7.53, -0.32, -11.02)
2:238903400	rs139283925	H>Y	A:37	(11.85, 0.72, 2.49)
2:238903412		P>A	A:41	(10.70, -9.58, 3.95)
2:238903419	rs574145639	K>T	A:43	(5.23, -7.94, 9.13)
2:238903428	rs367975107	C>Y	A:46	(2.85, -3.77, 7.40)
2:238903430	rs190497001	F>V	A:47	(3.71, -0.48, 3.04)
2:238903435		Q>H	A:48	(7.23, 1.98, 6.05)
2:238925246		T>A	A:67	(-0.58, 1.29, 4.11)
2:238925273	rs151092696	V>M	A:76	(-11.40, -4.91, 2.96)
2:238933997	rs371779701	K>N	A:81	(-1.19, 5.23, 10.75)
2:238939219		D>N	A:108	(-21.34, 8.44, -0.37)
2:238939222		G>S	A:109	(-20.42, 5.79, -3.49)
2:238940869		V>I	A:122	(-0.01, 5.12, -3.28)
2:238940881		N>D	A:126	(0.57, 11.91, -4.86)
2:238940893		T>A	A:130	(-1.36, 17.80, -6.05)
2:238944531		F>I	A:135	(-9.02, 23.99, 1.64)
2:238944574	COSM4092719	R>Q	A:149	(-6.84, 34.19, 8.69)
2:238949931		E>D	A:152	(-0.36, 34.83, 1.22)
2:238949938		R>G	A:155	(2.00, 30.74, 0.21)
2:238949960		I>N	A:162	(7.85, 21.44, 5.57)
2:238949965		R>C	A:164	(9.30, 23.64, 13.64)
2:238949966	COSM1018504	R>H	A:164	(9.30, 23.64, 13.64)

2EDI.A | UBE2F.