General Structure Information
| PDB ID | 3rq4 |
| HGNC Gene Label(s) | SUV420H2 |
| Structure Name | crystal structure of suppressor of variegation 4-20 homolog 2 |
| Resolution | 1.8Å |
| Reference | AUTH H.WU,A.SIARHEYEVA,H.ZENG,R.LAM,A.DONG,X.H.WU,Y.LI,AUTH 2 M.SCHAPIRA,M.VEDADI,J.MINTITL CRYSTAL STRUCTURES OF THE HUMAN HISTONE H4K20TITL 2 METHYLTRANSFERASES SUV420H1 AND SUV420H2.REF FEBS LETT. V. 587 3859 2013REFN ISSN 0014-5793PMID 24396869 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 240 |
| Number Of SNVs | 42 |
| Number Of Permutations | 16372 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.177 |
| p-value | 0.313 |
COSMIC
| Number Of Residues | 240 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.2 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.348 |
| p-value | 0.104 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
